Does intrathecal fentanyl provide benefit in patients undergoing cesarean delivery under spinal anesthesia?
Intrathecal fentanyl appears beneficial as an additive to bupivacaine for cesarean delivery under spinal anesthesia, though evidence is limited by bias and small sample sizes.
Current evidence suggests a benefit of using fentanyl as both an additive to intrathecal bupivacaine alone and to intrathecal bupivacaine combined with morphine for cesarean delivery under spinal anesthesia. The possibility of publication bias, small sample size, and high risk of bias in some of the included studies warrant treating the results with caution.
Uppal et al. (Tue,) studied this question.