Why the study?
Does intrathecal fentanyl provide benefit in patients undergoing cesarean delivery under spinal anesthesia?
Population
Patients undergoing cesarean delivery under spinal anesthesia
Comparison
Fentanyl as an additive to intrathecal bupivacaine alone or combined with morphine
Design
Systematic review and meta-analysis of randomized controlled trials with trial sequential analysis
Authors
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Supports adding intrathecal fentanyl to bupivacaine for cesarean spinal anesthesia; extends evidence for adjunctive use with or without morphine.
Does intrathecal fentanyl provide benefit in patients undergoing cesarean delivery under spinal anesthesia?
Intrathecal fentanyl appears beneficial as an additive to bupivacaine for cesarean delivery under spinal anesthesia, though evidence is limited by bias and small sample sizes.
Uppal et al. (2019) studied this question.