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Clustal Omega is a package for making multiple sequence alignments of amino acid or nucleotide sequences, quickly and accurately. It is a complete upgrade and rewrite of earlier Clustal programs. This unit describes how to run Clustal Omega interactively from a command line, although it can also be run online from several sites. The unit describes a basic protocol for taking a set of unaligned sequences and producing a full alignment. There are also protocols for using an external HMM or iteration to help improve an alignment.
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Sievers et al. (Mon,) studied this question.
www.synapsesocial.com/papers/69da9ad7615cc0c8eaa3c0f5 — DOI: https://doi.org/10.1002/0471250953.bi0313s48
Fabian Sievers
Desmond G. Higgins
Current Protocols in Bioinformatics
University College Dublin
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