Macrovasculature and Microvasculature at the Crossroads Between Type 2 Diabetes Mellitus and Hypertension

Diabetes mellitus (both type 1 and 2) affects an estimated 425 million people worldwide and if current trends continue, ≈693 million people (10% of the population) will have diabetes mellitus by 2045.1 Patients with type 2 diabetes mellitus (T2D) are at an increased risk of damage to target organs. The causes for these adverse changes are unknown, however, high blood pressure (BP) or hypertension, is likely to play a contributory role. Indeed, T2D and hypertension commonly coexist and may act synergistically to promote clinical events.