Does biologic therapy reduce coronary inflammation assessed by perivascular FAI in patients with moderate to severe psoriasis?
Patients with moderate to severe psoriasis
Biologic therapy
Coronary inflammation assessed by perivascular fat attenuation index (FAI) measured by CCTAsurrogate
Biologic therapy in psoriasis patients is associated with reduced coronary inflammation, suggesting perivascular FAI via CCTA could track responses to interventions for coronary artery disease.
In this study, biologic therapy for moderate to severe psoriasis was associated with reduced coronary inflammation assessed by perivascular FAI. This finding suggests that perivascular FAI measured by CCTA may be used to track response to interventions for coronary artery disease.
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Youssef Elnabawi
Cornell University
Evangelos K. Oikonomou
Cardiac Imaging
Amit K. Dey
University of Kalyani
JAMA Cardiology
National Institutes of Health
University of Oxford
University of Pennsylvania
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Elnabawi et al. (Wed,) studied this question.
synapsesocial.com/papers/69d56c2375589c71d767cc1b — DOI: https://doi.org/10.1001/jamacardio.2019.2589