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July 31, 2019JAMA Cardiology234 citationsOpen Access

Association of Biologic Therapy With Coronary Inflammation in Patients With Psoriasis as Assessed by Perivascular Fat Attenuation Index

YEYoussef ElnabawiEOEvangelos K. OikonomouADAmit K. Dey

Structured PICO

Does biologic therapy reduce coronary inflammation assessed by perivascular FAI in patients with moderate to severe psoriasis?

P
Population
Patients with moderate to severe psoriasis
I
Intervention
Biologic therapy
O
Outcome
Coronary inflammation assessed by perivascular fat attenuation index (FAI) measured by CCTAsurrogate

Biologic therapy in psoriasis patients is associated with reduced coronary inflammation, suggesting perivascular FAI via CCTA could track responses to interventions for coronary artery disease.

Abstract

In this study, biologic therapy for moderate to severe psoriasis was associated with reduced coronary inflammation assessed by perivascular FAI. This finding suggests that perivascular FAI measured by CCTA may be used to track response to interventions for coronary artery disease.

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Elnabawi et al. (2019) studied this question.

synapsesocial.com/papers/69d56c2375589c71d767cc1bhttps://doi.org/10.1001/jamacardio.2019.2589
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