What does this research mean for the field?

Patients with hypertrophic cardiomyopathy (HCM) without atrial fibrillation have an ischemic stroke risk comparable to the general population with atrial fibrillation, suggesting that oral anticoagulants may be necessary for this group. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

December 2, 2019Open Access

Risk of ischemic stroke in patients with hypertrophic cardiomyopathy in the absence of atrial fibrillation – a nationwide cohort study

TLTing‐Tse LinNational Taiwan University YSYen‐Ling SungCedars-Sinai Medical Center TKTsung‐Yu KoCardiovascular Research Center

Structured PICO

Does hypertrophic cardiomyopathy without atrial fibrillation increase the risk of ischemic stroke compared to controls?

Population

Patients with hypertrophic cardiomyopathy (HCM) in the absence of atrial fibrillation (AF)

Comparator

Control subjects and general population with atrial fibrillation

Outcome

Ischemic stroke (IS)hard clinical

Patients with hypertrophic cardiomyopathy without atrial fibrillation have an ischemic stroke risk comparable to the general population with atrial fibrillation, suggesting a potential role for oral anticoagulation.

Abstract

-VASc score, HCM subjects with score 0, 1 and 2 had significantly increased risk of IS than control while those with score ≥2 had similar risk as control. Compared with general population with AF, HCM patients without AF had similar risk of IS, suggesting OACs might be necessary in HCM patient without AF.

Ask AI

Helpful

Bookmark

View Full Paper