Risk of ischemic stroke in patients with hypertrophic cardiomyopathy in the absence of atrial fibrillation – a nationwide cohort study

Figure 1. Cumulative incidence function curves for ischemic stroke in different age groups. (A) Survival curve with the Fine and Gray test describing ischemic stroke among patients with HCM without AF and matched general population with AF. The Fine and Gray test showed no significant difference (P = 0.157). (B) Survival curve in the subgroup with age of 20-39 years. The Fine and Gray test showed no significant difference. (p=0.445). (C) Survival curve in the subgroup with age of 40-64 years. The Fine and Gray test showed no significant difference. (p=0.993). (D) Survival curve in the subgroup with age of 65-74 years. The Fine and Gray test showed significant difference. (p=0.005). (E) Survival curve in the subgroup with age above 75 years. The Fine and Gray test showed significant difference. (p < 0.001). Abbreviations: AF, atrial fibrillation; HCM, hypertrophic cardiomyopathy.

Figure 2. Annual risk of ischemic stroke in patients with HCM without AF and matched general population without AF.

Figure 3. Patient flow diagram. Abbreviations: AF, atrial fibrillation; HCM, hypertrophic cardiomyopathy; NHIRD, National health insurance research database.