Patients with atrial fibrillation (AF)
Direct oral anticoagulants (DOACs)
Adherence and persistence to DOACs
Suboptimal adherence to DOACs is common in real-world AF patients (1 in 3 patients having <80% adherence) and is associated with poor clinical outcomes, highlighting the need for better monitoring.
Suboptimal adherence and persistence to DOACs was common in patients with AF, with 1 in 3 patients adhering to their DOAC <80% of the time, which was associated with poor clinical outcomes in nonadherent patients. Although it is convenient that DOACs do not require laboratory monitoring, greater effort in monitoring for and interventions to prevent nonadherence may be necessary to optimize stroke prevention. Increased clinician awareness of DOAC nonadherence may help identify at-risk patients.
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Aya Ozaki
A. Choi
Quan Le
Circulation Cardiovascular Quality and Outcomes
University of California, Los Angeles
University Health Network
VA Greater Los Angeles Healthcare System
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Ozaki et al. (Sun,) studied this question.
www.synapsesocial.com/papers/69d572e0d9840517963cd69e — DOI: https://doi.org/10.1161/circoutcomes.119.005969