Do circulating lipoprotein lipids and apolipoproteins causally relate to the risk of coronary heart disease?
Circulating lipoprotein lipids and apolipoproteins (genetic proxies)
Risk of coronary heart disease (CHD)hard clinical
This Mendelian randomization analysis highlights apolipoprotein B as the predominant causal factor linking lipoprotein lipids to coronary heart disease risk.
These findings suggest that apolipoprotein B is the predominant trait that accounts for the aetiological relationship of lipoprotein lipids with risk of CHD.
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Tom G. Richardson
Preventive Cardiology
Eleanor Sanderson
Preventive Cardiology
Tom Palmer
University of Bristol
SHILAP Revista de lepidopterología
PLoS Medicine
University of Oxford
University of Cambridge
University of Bristol
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Richardson et al. (Mon,) studied this question.
synapsesocial.com/papers/69de8525353721b241b0c07a — DOI: https://doi.org/10.1371/journal.pmed.1003062