Do circulating lipoprotein lipids and apolipoproteins causally relate to the risk of coronary heart disease?
This Mendelian randomization analysis highlights apolipoprotein B as the predominant causal factor linking lipoprotein lipids to coronary heart disease risk.
These findings suggest that apolipoprotein B is the predominant trait that accounts for the aetiological relationship of lipoprotein lipids with risk of CHD.
Richardson et al. (Mon,) studied this question.