A custom watch-based device for noninvasive, cuff-less blood pressure estimation via pulse transit time correlated with 24-hour ambulatory BP (Pearson correlation coefficient 0.69; RMSE 2.72 mmHg).
Observational (n=21)
Does a wearable watch-based device using pulse transit time accurately estimate blood pressure compared to a standard oscillometric cuff in healthy subjects?
A custom wearable watch using pulse transit time provides reasonably accurate, cuff-less blood pressure estimation at home, offering a convenient alternative for ambulatory blood pressure monitoring.
Effect estimate: PCC 0.69; RMSE 2.72 mmHg
OBJECTIVE: We developed a wearable watch-based device to provide noninvasive, cuff-less blood pressure (BP) estimation in an at-home setting. METHODS: The watch measures single-lead electrocardiogram (ECG), tri-axial seismocardiogram (SCG), and multi-wavelength photoplethysmogram (PPG) signals to compute the pulse transit time (PTT), allowing for BP estimation. We sent our custom watch device and an oscillometric BP cuff home with 21 healthy subjects, and captured the natural variability in BP over the course of a 24-hour period. RESULTS: After calibration, our Pearson correlation coefficient (PCC) of 0.69 and root-mean-square-error (RMSE) of 2.72 mmHg suggest that noninvasive PTT measurements correlate with around-the-clock BP. Using a novel two-point calibration method, we achieved a RMSE of 3.86 mmHg. We further demonstrated the potential of a semi-globalized adaptive model to reduce calibration requirements. CONCLUSION: This is, to the best of our knowledge, the first time that BP has been comprehensively estimated noninvasively using PTT in an at-home setting. We showed a more convenient method for obtaining ambulatory BP than through the use of the standard oscillometric cuff. We presented new calibration methods for BP estimation using fewer calibration points that are more practical for a real-world scenario. SIGNIFICANCE: A custom watch (SeismoWatch) capable of taking multiple BP measurements enables reliable remote monitoring of daily BP and paves the way towards convenient hypertension screening and management, which can potentially reduce hospitalizations and improve quality of life.
Ganti et al. (Thu,) conducted a observational in Healthy (n=21). Wearable watch-based device (SeismoWatch) vs. Oscillometric BP cuff was evaluated on Blood pressure estimation accuracy (PCC 0.69; RMSE 2.72 mmHg). A custom watch-based device for noninvasive, cuff-less blood pressure estimation via pulse transit time correlated with 24-hour ambulatory BP (Pearson correlation coefficient 0.69; RMSE 2.72 mmHg).
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