Continuous positive airway pressure (CPAP) treatment for obstructive sleep apnea reduces the cardio-ankle vascular index (CAVI), a blood pressure-independent measure of arterial stiffness.
Does continuous positive airway pressure (CPAP) improve cardio-ankle vascular index (CAVI) in patients with obstructive sleep apnea?
CAVI is a useful, blood pressure-independent marker of arterial stiffness that correlates with OSA severity and can be improved by CPAP therapy.
Patients with obstructive sleep apnea (OSA) are susceptible to developing atherosclerosis. Consequently, such patients are at a high risk of developing cardiovascular diseases, leading to poor prognosis. Many physiological parameters have been previously used to predict the development of atherosclerosis. One such parameter, the cardio-ankle vascular index (CAVI), a measure of arterial stiffness, has garnered much attention as it can also predict the degree of atherosclerosis. The CAVI can be calculated based on noninvasive measurements, and is less susceptible to blood pressure variations at the time of measurement. Therefore, the CAVI can assess changes in arterial stiffness and the risk of developing atherosclerosis independent of blood pressure changes. Continuous positive airway pressure (CPAP) is a standard therapy for OSA and can suppress the issue significantly. Several studies have shown that CPAP treatment for OSA could also reduce the CAVI. In this review, we discuss the relationship between OSA and arterial stiffness, primarily focusing on the CAVI. Furthermore, we propose future perspectives for the CAVI and OSA.
Tomita et al. (Wed,) conducted a review in Obstructive sleep apnea. Continuous positive airway pressure (CPAP) was evaluated. Continuous positive airway pressure (CPAP) treatment for obstructive sleep apnea reduces the cardio-ankle vascular index (CAVI), a blood pressure-independent measure of arterial stiffness.