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Atherosclerotic Carotid Plaque Composition and Incident Stroke and Coronary Events | Synapse

March 1, 2021Open Access

Atherosclerotic Carotid Plaque Composition and Incident Stroke and Coronary Events

Structured PICO

Does the presence of IPH in the carotid atherosclerotic plaque predict incident stroke and CHD in healthy persons with subclinical atherosclerosis?

P

Population

Healthy persons with subclinical atherosclerosis

I

Intervention

Presence of intraplaque hemorrhage (IPH) in the carotid atherosclerotic plaque

O

Outcome

Incident stroke and coronary heart disease (CHD)hard clinical

Intraplaque hemorrhage in carotid atherosclerotic plaques is an independent risk factor for stroke and CHD, showing promise as a marker of plaque vulnerability.

Abstract

The presence of IPH in the carotid atherosclerotic plaque is an independent risk factor for stroke and CHD. These findings indicate the promise of IPH as a marker of plaque vulnerability in healthy persons with subclinical atherosclerosis.

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Authors

D

Daniël Bos

B

Banafsheh Arshi

Q

Quirijn J.A. van den Bouwhuijsen

Journals

Journal of the American College of Cardiology

Actions

Institutions

Erasmus MC

References and Citations

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Cite this study

Bos et al. (Mon,) studied this question.

www.synapsesocial.com/papers/69b98c3956563fbd68cf3e90 — DOI: https://doi.org/10.1016/j.jacc.2021.01.038

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North American Symptomatic Carotid Endarterectomy Trial. Methods, patient characteristics, and progress.· 1991 · 1,133 citations
Correlation of computed tomography with carotid plaque transcriptomes associates calcification with lesion-stabilization· 2019 · 77 citations
Carotid intima-media thickness at different sites: relation to incident myocardial infarction. The Rotterdam Study· 2002 · 221 citations