Does dual antiplatelet therapy reduce ischemic stroke recurrence compared to aspirin monotherapy in patients with acute minor ischemic stroke or TIA?
Patients with acute minor ischemic stroke or transient ischemic attack (TIA)
Dual antiplatelet therapy (DAPT)
Aspirin monotherapy
Ischemic stroke recurrencehard clinical
In patients with acute minor ischemic stroke or TIA, DAPT reduces ischemic stroke recurrence but increases major bleeding compared to aspirin monotherapy.
Among patients with acute minor ischemic stroke or TIA, DAPT, as compared with aspirin monotherapy, might offer better effectiveness in terms of ischemic stroke recurrence at the expense of a higher risk of major bleeding. The trade-off between ischemic benefits and bleeding risks should be assessed in tailoring the therapeutic strategies.
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Francesco Condello
Gaetano Liccardo
Giuseppe Ferrante
Current Pharmaceutical Design
IRCCS Humanitas Research Hospital
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Condello et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69a3048a5406085704ad98bb — DOI: https://doi.org/10.2174/1381612827666210728102459
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