Coronary artery revascularization (CABG or PCI) had inconsistent associations with cognitive decline or dementia across four reviewed studies due to heterogeneous outcome measurements.
Systematic Review (n=4)
Does coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) prevent cognitive decline or dementia in persons with CAD?
There is currently insufficient and inconsistent evidence to determine the long-term effects of coronary revascularization on cognitive decline and dementia.
Coronary artery disease (CAD) is a risk factor for cognitive decline. The aim of this study was to systematically review recent literature on whether coronary artery revascularizations are associated to cognitive decline and dementia. Pubmed, Scopus, and CINAHL (EBSCO) were searched systematically from January 2009 to September 2020. Studies were conducted on persons with CAD undergoing coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) procedure compared to other coronary artery disease treatments, and the outcome was cognitive decline or dementia. Altogether four of the 680 reviewed articles met inclusion criteria. Results were inconsistent, and the outcome measurements heterogeneous between studies. Our findings indicate an evidence gap in the current understanding of long-term outcomes following coronary artery revascularization. However, evidence of long-term effects on cognition would complement our understanding of their benefits. There is a need for more studies on long-term cognitive outcomes after coronary artery revascularizations.
Lappalainen et al. (Wed,) conducted a systematic review in Coronary artery disease (n=4). Coronary artery revascularization (CABG or PCI) vs. Other coronary artery disease treatments was evaluated on Cognitive decline or dementia. Coronary artery revascularization (CABG or PCI) had inconsistent associations with cognitive decline or dementia across four reviewed studies due to heterogeneous outcome measurements.