Key result
Coronary artery revascularization (CABG or PCI) had inconsistent associations with cognitive decline or dementia across four reviewed studies due to heterogeneous outcome measurements.
Why the study?
CAD is a risk factor for cognitive decline, and the association between coronary artery revascularizations and subsequent cognitive decline or dementia needed systematic evaluation.
Does coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) prevent cognitive decline or dementia in persons with CAD?
Population
Persons with CAD across four included studies
Comparison
CABG or PCI procedure vs other CAD treatments
Design
Systematic review
Authors
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Insufficient evidence precludes using revascularization for cognitive protection; leaves open dementia effects pending standardized trials.
Systematic Review (n=4)
Does coronary artery bypass grafting (CABG) or percutaneous coronary intervention (PCI) prevent cognitive decline or dementia in persons with CAD?
There is currently insufficient and inconsistent evidence to determine the long-term effects of coronary revascularization on cognitive decline and dementia.
Lappalainen et al. (2021) conducted a systematic review in Coronary artery disease (n=4). Coronary artery revascularization (CABG or PCI) vs. Other coronary artery disease treatments was evaluated on Cognitive decline or dementia. Coronary artery revascularization (CABG or PCI) had inconsistent associations with cognitive decline or dementia across four reviewed studies due to heterogeneous outcome measurements.
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