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In this trial involving patients with HER2-low metastatic breast cancer, trastuzumab deruxtecan resulted in significantly longer progression-free and overall survival than the physician's choice of chemotherapy. (Funded by Daiichi Sankyo and AstraZeneca; DESTINY-Breast04 ClinicalTrials.gov number, NCT03734029.).
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Shanu Modi
William Jacot
Toshinari Yamashita
New England Journal of Medicine
University of California, San Francisco
Inserm
Memorial Sloan Kettering Cancer Center
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Modi et al. (Sun,) studied this question.
www.synapsesocial.com/papers/69d6f9a9f174babf6cab3c90 — DOI: https://doi.org/10.1056/nejmoa2203690