A modified Japanese version of the High Bleeding Risk (J-HBR) score ≥1.5 significantly predicted major bleeding at 1 year (HR 3.81) without an increased risk of ischemic events.
Observational (n=842)
No
Does the J-HBR score correlate with the PRECISE-DAPT score and predict major bleeding and ischemic events in patients undergoing PCI?
A modified J-HBR score cutoff of ≥1.5 identifies patients at high bleeding risk without an increased risk of ischemic events, offering a potential tool for tailoring antithrombotic therapy post-PCI.
Hazard Ratio: 3.81 (95% CI 1.43–10.15)
p-value: p=0.007
Background: The correlation between the Japanese version of high bleeding risk (J-HBR) criteria and the Predicting Bleeding Complications in Patients Undergoing Stent Implantation and Subsequent Dual Antiplatelet Therapy (PRECISE-DAPT) score is unknown, as is the relationship of both risk scores with ischemic events.
Kubota et al. (2022) conducted an observational in Patients undergoing percutaneous coronary intervention (PCI) (n=842). J-HBR score ≥1.5 vs. J-HBR score <1.5 was evaluated on Major bleeding at 1 year (HR 3.81, 95% CI 1.43-10.15, p=0.007). A modified Japanese version of the High Bleeding Risk (J-HBR) score ≥1.5 significantly predicted major bleeding at 1 year (HR 3.81) without an increased risk of ischemic events.