Key result
A modified Japanese version of the High Bleeding Risk (J-HBR) score ≥1.5 significantly predicted major bleeding at 1 year (HR 3.81) without an increased risk of ischemic events.
Why the study?
The correlation between the J-HBR criteria and the PRECISE-DAPT score, as well as their relationship with ischemic events, was unknown.
Does the J-HBR score correlate with the PRECISE-DAPT score and predict major bleeding and ischemic events in patients undergoing PCI?
Observational (n=842)
No
Does the J-HBR score correlate with the PRECISE-DAPT score and predict major bleeding and ischemic events in patients undergoing PCI?
A modified J-HBR score cutoff of ≥1.5 identifies patients at high bleeding risk without an increased risk of ischemic events, offering a potential tool for tailoring antithrombotic therapy post-PCI.
May support post-PCI bleeding risk stratification; hypothesis-generating and requires prospective validation before practice change.
Background: The correlation between the Japanese version of high bleeding risk (J-HBR) criteria and the Predicting Bleeding Complications in Patients Undergoing Stent Implantation and Subsequent Dual Antiplatelet Therapy (PRECISE-DAPT) score is unknown, as is the relationship of both risk scores with ischemic events.
No takes yet. Share an insight, caveat, or question.
Kubota et al. (2022) conducted an observational in Patients undergoing percutaneous coronary intervention (PCI) (n=842). J-HBR score ≥1.5 vs. J-HBR score <1.5 was evaluated on Major bleeding at 1 year (HR 3.81, 95% CI 1.43-10.15, p=0.007). A modified Japanese version of the High Bleeding Risk (J-HBR) score ≥1.5 significantly predicted major bleeding at 1 year (HR 3.81) without an increased risk of ischemic events.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: