Key points are not available for this paper at this time.
Kido S, Ikezoe J, Naito H, Tamura S, Kozuka T, Ito W, Shimura K, Kato H. Single-exposure dual-energy chest images with computed radiography: evaluation with simulated pulmonary nodules. Invest Radiol 1993;28:482–487. RATIONALE AND OBJECTIVES. Dual-energy subtraction radiography using computed radiography (CR) can aid in the detection of pulmonary abnormalities such as nodules, but the subtracted image requires higher x-ray exposure than usual to reduce quantum mottle. To reduce quantum mottle without increasing x-ray exposure, a new dual-energy subtraction algorithm was investigated that included an edge-adaptive smoothing process and a subtraction process. The signal-to-noise ratio and the image quality of this new subtracted image was significantly superior to that of conventional subtracted images. METHODS. Observer performance of the subtracted digital radiography in detecting simulated pulmonary nodules was compared with original CR images and conventional subtracted digital radiography of 50 patients. RESULTS. A combination of an original CR image and a new subtracted CR image was significantly superior to a single original CR image or a combination of an original CR image and a conventional subtracted CR image (P < .01). DISCUSSION. The single-exposure dual-energy subtraction method is superior to the conventional subtraction method in the detection of pulmonary nodules.
Kido et al. (Tue,) studied this question.