Key points are not available for this paper at this time.
Therapeutic effect of phytochemicals has been emphasized in the traditional medicine owing to the presence of bioactive molecules, such as polyphenols. Luteolin is a flavone belonging to the flavonoid class of polyphenolic phytochemicals with healing effect on hypertension, inflammatory disorders, and cancer due to its action as pro-oxidants and antioxidants. The anticancer profile of luteolin is of interest due to the toxic effect of contemporary chemotherapy paradigm, leading to the pressing need for the development and identification of physiologically benevolent anticancer agents and molecules. Luteolin exerts anticancer activity by downregulation of key regulatory pathways associated with oncogenesis, in addition to the induction of oxidative stress, cell cycle arrest, upregulation of apoptotic genes, and inhibition of cell proliferation and angiogenesis in cancer cells. In this review, we discuss about the anticancer profile of luteolin.
Building similarity graph...
Analyzing shared references across papers
Loading...
Parteek Prasher
Mousmee Sharma
Sachin Kumar Singh
Cancer Cell International
University of Technology Sydney
Pontificia Universidad Católica de Chile
Lovely Professional University
Building similarity graph...
Analyzing shared references across papers
Loading...
Prasher et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69ff48bce92f4a033c8523c7 — DOI: https://doi.org/10.1186/s12935-022-02808-3