Clot-in-transit can embolize to the pulmonary circulation in seconds and be immediately fatal, requiring emergent management based on multidisciplinary discussion.
Case Report (n=2)
Clot-in-transit is a highly unstable condition that can rapidly embolize, highlighting the need for emergent multidisciplinary pulmonary embolism response team (PERT) evaluation.
Clot-in-transit is associated with severe pulmonary embolism and higher mortality than acute pulmonary embolism without clot-in-transit. The optimal treatment of clot-in-transit is not established. Multiple treatment options have been described, including anticoagulation alone, systemic thrombolysis, surgical embolectomy and endovascular catheter-based therapies. Clot-in-transit can embolize to the pulmonary circulation in a matter of seconds and be immediately fatal. We describe two cases of clot-in-transit which embolized quickly upon Intensivist's evaluation and were associated with serious consequences. Management decisions for clot-in-transit should be emergent and based on multidisciplinary discussion of the pulmonary embolism response team.
Igwilo et al. (Sun,) conducted a case report in Clot-in-transit (n=2). Clot-in-transit was evaluated on Embolization to the pulmonary circulation and serious consequences. Clot-in-transit can embolize to the pulmonary circulation in seconds and be immediately fatal, requiring emergent management based on multidisciplinary discussion.