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Platelet-Derived MicroRNAs Regulate Cardiac Remodeling After Myocardial Ischemia | Synapse

March 9, 2023Open Access

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Platelet-Derived MicroRNAs Regulate Cardiac Remodeling After Myocardial Ischemia

JSJan Philipp SchütteHeidelberg University MMMailin-Christin MankeVascular Medicine KHKatherina HemmenUniversity of Würzburg

Structured PICO

Do platelet-derived miRNAs regulate cardiac remodeling and inflammation after myocardial ischemia/reperfusion?

P

Population

Myocardial ischemia/reperfusion (I/R) model

I

Intervention

Platelet-derived miRNA

O

Outcome

Myocardial inflammation and structural remodelingsurrogate

Platelet-derived miRNAs are critically involved in regulating myocardial inflammation and structural remodeling after ischemia/reperfusion injury.

Abstract

The present study discloses a critical role of platelet-derived miRNA in myocardial inflammation and structural remodeling processes following myocardial I/R.

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Cite This Study

Schütte et al. (Thu,) studied this question.

synapsesocial.com/papers/69dc0cd70648942b0a9c7ce6 https://doi.org/https://doi.org/10.1161/circresaha.122.322459