Abnormal conduction, such as left bundle branch block and pre-excitation, can induce reversible cardiomyopathies that improve with appropriate diagnosis and treatment.
Nonischemic cardiomyopathies are a frequent occurrence. The understanding of the mechanism(s) and triggers of these cardiomyopathies have led to improvement and even recovery of LV function. While chronic right ventricular pacing-induced cardiomyopathy has been recognized for many years, left bundle branch block (LBBB) and pre-excitation have been recently identified as potential reversible causes of cardiomyopathy. These cardiomyopathies share a similar abnormal ventricular propagation that can be recognized by a wide QRS duration with LBBB pattern and thus we coin the term “abnormal conduction-induced cardiomyopathies”. Such abnormal propagation results in an abnormal contractility that can only be recognized by cardiac imaging as ventricular dyssynchrony. Appropriate diagnosis and treatment will not only lead to improved LVEF and functional class but may also reduce morbidity and mortality. This manuscript presents an update of the mechanisms, prevalence, incidence, risk factors, as well as their diagnosis and management, while highlighting current gaps of knowledge.
Huizar et al. (Wed,) conducted a review in Abnormal conduction-induced cardiomyopathy. Abnormal conduction (LBBB, RV pacing, pre-excitation) was evaluated. Abnormal conduction, such as left bundle branch block and pre-excitation, can induce reversible cardiomyopathies that improve with appropriate diagnosis and treatment.