Cardiac magnetic resonance and transthoracic echocardiography showed excellent agreement for aortic valve area measurements (ICC 0.932; 95% CI 0.829-0.973) in severe aortic stenosis.
Observational
Does cardiac magnetic resonance provide comparable aortic valve area and strain measurements to transthoracic echocardiography in patients with severe aortic stenosis and normal left ventricular function?
CMR and TTE show good agreement for measuring aortic valve area and myocardial strain in patients with severe aortic stenosis and normal LV function.
Effect estimate: ICC 0.932 (95% CI 0.829-0.973)
p-value: p=<0.05
Background: Transthoracic echocardiography (TTE) is the recommended imaging technique for the evaluation of patients with aortic stenosis (AS). However, in cases with inconclusive findings, cardiac magnetic resonance (CMR) planimetry is used to grade AS severity. This study aimed to compare the results derived from TTE and CMR in patients with severe AS with normal left ventricular (LV) function. Methods: test, intraclass correlation coefficient (ICC), and Pearson correlation. P<0.05 was considered statistically significant. Results: An excellent agreement was found in AVA values derived from CMR and TTE with an average ICC of 0.932 (95% CI=0.829-0.973). There was a significant difference in LV-GLS, LV global radial strain (GRS), right ventricular (RV) GRS, and RV global circumferential strain between the groups. A good correlation was found between CMR- and TTE-derived GLS with an average ICC of 0.721 (95% C=0.255-0.896). The mean aortic valve pressure gradient in TTE had a significant inverse linear correlation with LV-GRS in CMR (r=-0.537). All P values were <0.05. Conclusion: There was a good agreement between AVA and strain values derived from cardiac MRI and TTE. The myocardial strain was impaired in patients with severe AS and normal LV function and correlated with disease severity.
Rezaeian et al. (Sat,) conducted a observational in Severe aortic stenosis with normal left ventricular function. Cardiac magnetic resonance (CMR) vs. Transthoracic echocardiography (TTE) was evaluated on Agreement in aortic valve area (AVA) values (ICC 0.932, 95% CI 0.829-0.973, p=<0.05). Cardiac magnetic resonance and transthoracic echocardiography showed excellent agreement for aortic valve area measurements (ICC 0.932; 95% CI 0.829-0.973) in severe aortic stenosis.
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