January 1, 2024Open Access
Coronary spasm and vasomotor dysfunction as a cause of MINOCA
Key Result
Coronary spasm and vasomotor dysfunction may be the underlying cause in more than half of myocardial infarctions with non-obstructive coronary arteries (MINOCA) and chronic chest pain.
Structured PICO
P
Population
Patients with myocardial infarction with non-obstructive coronary arteries (MINOCA) or chronic chest pain
Coronary spasm and vasomotor dysfunction are increasingly recognized as the underlying cause in over half of MINOCA cases.
Abstract
Increasing evidence has shown that coronary spasm and vasomotor dysfunction may be the underlying cause in more than half of myocardial infarctions with non-obstructive coronary arteries (MINOCA) as well as an important cause of chronic chest pain in the outpatient setting. We review the contemporary understanding of coronary spasm and related vasomotor dysfunction of the coronary arteries, the pathophysiology and prognosis, and current and emerging approaches to diagnosis and evidence-based treatment.