Impact of antiretroviral therapy during acute or early HIV infection on virologic and immunologic outcomes: results from a multinational clinical trial

Key Points

• ART initiation during acute HIV infection improves virologic and immunologic outcomes significantly.
• Findings indicate that timely treatment can enhance host immune responses and reduce the viral reservoir.
• Assessment in a multinational clinical trial underscores the importance of early therapeutic interventions in HIV patients across various locations and demographics. The results may enable earlier diagnosis and treatment of acute HIV infections to improve long-term health outcomes.