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SQANTI3 is a tool designed for the quality control, curation and annotation of long-read transcript models obtained with third-generation sequencing technologies. Leveraging its annotation framework, SQANTI3 calculates quality descriptors of transcript models, junctions and transcript ends. With this information, potential artifacts can be identified and replaced with reliable sequences. Furthermore, the integrated functional annotation feature enables subsequent functional iso-transcriptomics analyses.
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Francisco J. Pardo-Palacios
Breast Cancer Research Foundation
Ángeles Arzalluz-Luque
Instituto de Neurociencias
Liudmyla Kondratova
University of Florida
Nature Methods
University of Florida
Universitat Politècnica de València
Pacific Biosciences (United States)
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Pardo-Palacios et al. (Wed,) studied this question.
synapsesocial.com/papers/68e732b8b6db6435876aba43 — DOI: https://doi.org/10.1038/s41592-024-02229-2
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