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Abstract objective Bone and muscle diseases are both highly prevalent in aging adults but results from previous studies examining the relationship between sarcopenia and its components with osteoporosis are inconsistent. This study aimed to evaluate the association between sarcopenia and its components with osteoporosis in elderly postmenopausal women. Materials p < 0.001), and between appendicular lean mass index (ALMI) and total hip BMD (r = 0.36; p < 0.001). Significant differences were observed between sub-groups of osteoporotic status: the handgrip strength, short physical performance battery (SPPB) test, gait speed, and ALMI were significantly lower in osteoporotic subjects (p < 0.001). After adjustment for all covariates, handgrip strength and gait speed were still significantly associated with osteoporosis with an odds ratio of 0.92 (0.88–0.97) and 0.33 (0.11–0.96), respectively. Handgrip strength under 16 kg showed a 2.2-fold higher risk of osteoporosis after adjustment for all covariates. Conclusion Sarcopenia, as defined by EWGSOP2, and its components, particularly handgrip strength and gait speed, were significantly associated with osteoporosis. The trabecular bone score, a surrogate for bone microarchitecture, was also significantly associated with all sarcopenia components. Therefore, it should be taken into consideration when evaluating bone health and fracture risk in routine geriatric clinical practice.
Tchang et al. (Thu,) studied this question.