Pd09-07 Spatial Transcriptomic Signature From Mutated Benign Ancestral Clone Predicts High Risk Prostate Cancer

You have accessJournal of UrologyProstate Cancer: Basic Research 95% CI 0.693-0.921). CONCLUSIONS: Our study demonstrates the predictive significance of spatially informed transcriptomic changes within histologically benign ancestral clones that give rise to clinically significant PCa. Our model has good performance for predicting high-risk disease from matched normal or low risk PCa tissue. This offers the translational possibility of predicting un-sampled high-risk disease from histologically benign biopsy cores. Download PPT Source of Funding: NIHR UK - Academic Clinical Fellowship Funding for Thineskrishna Anbarasan © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e181 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Thineskrishna Anbarasan More articles by this author Wencheng Yin More articles by this author Sandy Figiel More articles by this author Ian Mills More articles by this author Alastair Lamb More articles by this author Expand All Advertisement PDF downloadLoading ...