Mp45-08 the Impact of Kidney Stone Disease on Quality of Life in High-Risk Stone Formers

You have accessJournal of UrologyStone Disease: Epidemiology & Evaluation II (MP45)1 May 2024MP45-08 THE IMPACT OF KIDNEY STONE DISEASE ON QUALITY OF LIFE IN HIGH-RISK STONE FORMERS Anis Assad, Brendan L. Raizenne, Mohamed E. M. El Yamani, Saud Almousa, Seth K. Bechis, Roger L. Sur, Stephen Y. Nakada, Necole M. M. Streeper, Sri Sivalingam, Vernon M. Pais, Ben H. Chew, Vincent G. Bird, Sero Andonian, Kristina L. Penniston, and Naeem Bhojani Anis AssadAnis Assad , Brendan L. RaizenneBrendan L. Raizenne , Mohamed E. M. El YamaniMohamed E. M. El Yamani , Saud AlmousaSaud Almousa , Seth K. BechisSeth K. Bechis , Roger L. SurRoger L. Sur , Stephen Y. NakadaStephen Y. Nakada , Necole M. M. StreeperNecole M. M. Streeper , Sri SivalingamSri Sivalingam , Vernon M. PaisVernon M. Pais , Ben H. ChewBen H. Chew , Vincent G. BirdVincent G. Bird , Sero AndonianSero Andonian , Kristina L. PennistonKristina L. Penniston , and Naeem BhojaniNaeem Bhojani View All Author Informationhttps://doi.org/10.1097/01.JU.0001008764.86460.8e.08AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: To assess the impact of kidney stone disease and its treatment on the health-related quality of life of high-risk stone formers with hyperparathyroidism, renal tubular acidosis, malabsorptive disease and medullary sponge kidney. METHODS: The Wisconsin Stone Quality of Life Questionnaire (WISQOL) was used to evaluate health-related quality of life in 3,301 patients with a history of kidney stone disease from 16 institutions in North America between 2014 and 2020. Baseline characteristics and medical history were collected from patients while active kidney stone disease was confirmed through radiological imaging. The high-risk group was compared to the remaining patients (control group) using Wilcoxon rank sum test. RESULTS: Of 1,499 patients with active kidney stone disease included in the study, the high-risk group included 120 patients. The high-risk group had significantly lower health-related quality of life scores compared to the control group (p<0.01). In the multivariable analyses, medullary sponge kidney disease and renal tubular acidosis were independent predictors of poorer health-related quality of life, while alkali therapy was an independent predictor of better health-related quality of life (all p<0.01). CONCLUSIONS: Among patients with active kidney stone disease, high-risk stone formers had impaired health-related quality of life with medullary sponge kidney disease and renal tubular acidosis being independent predictors of poorer health-related quality of life. Clinicians should seek to identify these patients earlier as they would benefit from prompt treatment and prevention. Download PPT Source of Funding: None © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e745 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Anis Assad More articles by this author Brendan L. Raizenne More articles by this author Mohamed E. M. El Yamani More articles by this author Saud Almousa More articles by this author Seth K. Bechis More articles by this author Roger L. Sur More articles by this author Stephen Y. Nakada More articles by this author Necole M. M. Streeper More articles by this author Sri Sivalingam More articles by this author Vernon M. Pais More articles by this author Ben H. Chew More articles by this author Vincent G. Bird More articles by this author Sero Andonian More articles by this author Kristina L. Penniston More articles by this author Naeem Bhojani More articles by this author Expand All Advertisement PDF downloadLoading ...