Mp12-05 Relative Impact of Urinary Conditions on Overall Quality of Life

You have accessJournal of UrologyHealth Services Research: Practice Patterns, Quality of Life and Shared Decision Making I (MP12)1 May 2024MP12-05 RELATIVE IMPACT OF URINARY CONDITIONS ON OVERALL QUALITY OF LIFE Vishrudh Vasudevan, Rodney L. Dunn, Martin Miner, Claus Roehrborn, Allen Seftel, Cathie Spino, John T. Wei, and Aruna Sarma Vishrudh VasudevanVishrudh Vasudevan , Rodney L. DunnRodney L. Dunn , Martin MinerMartin Miner , Claus RoehrbornClaus Roehrborn , Allen SeftelAllen Seftel , Cathie SpinoCathie Spino , John T. WeiJohn T. Wei , and Aruna SarmaAruna Sarma View All Author Informationhttps://doi.org/10.1097/01.JU.0001009376.16371.fb.05AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: To compare the impact of lower urinary tract symptoms (LUTS) attributable to benign prostatic hyperplasia (BPH) and other urinary conditions to other comorbidities on quality of life (QoL) after adjustment for lifestyle/demographic characteristics. METHODS: The BPH Registry and Patient Survey is a multicenter, longitudinal, observational database of management practices and patient outcomes in a population of 6,823 patients with BPH in the USA, managed with watchful waiting or pharmacotherapy. QoL was assessed using the Medical Outcomes Study-Short Form 12 physical (SF-12 PCS) and mental health (SF-12 MCS) component scores. The following urinary conditions were evaluated: lower urinary tract symptoms (LUTS) assessed using the International Prostate Symptom Score (IPSS), physician diagnosed urinary incontinence (UI), overactive bladder (OAB) and urinary tract infection (UTI). Associations between QoL and urinary conditions and other comorbidities adjusted for demographic/lifestyle factors were estimated using linear regression models. RESULTS: 21.1% of the population reported having at least one urinary condition; however, prevalence of individual urinary conditions was less than other comorbidities. After adjustment for age, marital status, education, income, employment, alcohol use and smoking status, severe LUTS (IPSS³20) and UI were associated with a 3.9 and 2.9 point lower SF-12 PCS, respectively. These were similar to the associations observed with arthritis and depression and more than the PCS reduction associated with CVD, cancer and diabetes. Urinary conditions were also associated with greater SF-12 MCS reductions compared to other co-morbidities. Only depression was associated with a greater reduction in SF-12 MCS. CONCLUSIONS: These findings demonstrate that the magnitude of the effects of urinary conditions, specifically LUTS and UI on QoL is comparable if not greater than other major chronic diseases with significant impact not only on the physical component of QoL but also on the mental domains. Source of Funding: This research was supported by contracts with Sanofi-Aventis © 2024 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 211Issue 5SMay 2024Page: e201 Advertisement Copyright & Permissions© 2024 by American Urological Association Education and Research, Inc.Metrics Author Information Vishrudh Vasudevan More articles by this author Rodney L. Dunn More articles by this author Martin Miner More articles by this author Claus Roehrborn More articles by this author Allen Seftel More articles by this author Cathie Spino More articles by this author John T. Wei More articles by this author Aruna Sarma More articles by this author Expand All Advertisement PDF downloadLoading ...