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Abstract Background: The role of vitamin D in the pathogenesis of rheumatoid arthritis is controversial. This study aims to assess the relation between vitamin D level and rheumatoid arthritis disease activity.Patients and methods: This study was conducted on 80 rheumatoid arthritis (RA) patients beside 40 healthy persons. Vitamin D level was assessed in all participants. Rheumatoid activity was assessed using DAS28 (disease activity score). RA patients were classified according to DAS 28 into two groups: active group and remission group.Results: The median for vitamin D level in RA group was 23.5ng/ml. There was no statistically significant difference in serum vitamin D level between RA cases and control group (23.5ng/ml versus 25ng/ml, P 0.9). Serum vitamin D level was not significantly different between active RA patients and patients in remission (P = 0.09 respectively). There was no significant difference between patients with different levels of vitamin D as regards activity parameters. No correlation was found between vitamin D level and rheumatoid activity.Conclusion: There was no difference in vitamin D level between RA patients and healthy control. Also, there was no difference in vitamin D level between RA patients with active disease and patients in remission. There was no significant association between vitamin D level and disease activity parameters.
Salem et al. (Fri,) studied this question.