Periodic Analytical Study of Punarnavastaka Kwatha With and Without Added Preservatives WSR to Shelf Life, Alkaloids, and Phytochemical Constituents

Excellent medicine is essential for disease prevention, treatment, and health maintenance.The process through which a drug or its combination is transformed into a useful medicinal form is known as aushadha kalpana (medical preparation) and it includes Panchavidha Kashaya Kalpana.Among all these fundamental treatments, kwatha kalpana is frequently utilized by Ayurvedic doctors; as a result, various kwathas are produced by pharmaceutical companies for profit.Preservatives are added to increase shelf life due to Kwatha's are more susceptible to microbial contamination and also helps to prevent microbial degradation and change during storage.Nowadays, sodium benzoate, methyl paraben, and propyl paraben are the stabilizing agents that are most frequently used in Kwatha Kalpana.According to Ayurvedic literature, the shelf life of Kwatha Kalpana is Sadhyosevana, which is due to the degradation of alkaloids and phytochemicals over time.Aim-To know the scientific evidence for mentioning Sadhyosevana for Kwatha Kalpana.Material and Methods-2 samples will be taken for the study.Sample 1: -Punarnavastaka Kwatha prepared as per classical reference.Sample 2: -Punarnavastaka Kwatha collected from GMP Certified Pharmacy.Assessment-All the samples will be analyzed by Analytical and pharmaceutical tests to see the outcomes of chemical changes and stability to the time (at 0 hours, 1 hour, 3hour & 24 hours).