Key points are not available for this paper at this time.
Background: Cutaneous adverse drug reactions (CADR) are being frequently reported.However, there is a paucity of epidemiological data in the Indian setting.We aimed to determine the frequency of cutaneous ADR in our setup, identify the causative drug(s), and evaluate their treatment response.Materials and methods: We included the retrospective data of 40 patients with cutaneous drug reactions.Available history including medication history was taken and causality was determined.Descriptive statistics were used for data analysis.Results: The most common offending drugs were antimicrobials followed by non-steroidal anti-inflammatory drugs (NSAIDs)/DMARDs.Among antimicrobials, fluoroquinolones were the commonest culprit.The maculopapular rash was the commonest manifestation seen in 50% of cases followed by fixed drug eruption (FDE) in 15% of total cases.Three cases of Stevens-Johnson Syndrome (SJS) were noted in our study.Levofloxacin was the offending drug in one case and rest two cases were due to cephalosporins. Conclusion:Awareness is needed about the common causative agents of CADR, and these drugs must not be prescribed irrationally.Detailed medication history and clinico-pharmacological evaluation are extremely important for approaching any patient with CADR.
Podder et al. (Sat,) studied this question.