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Herbal remedies serve as complementary and alternative treatments to allopathic medications, which are thought to have unfavourable side effects.Through lipid peroxidation, oxidation is thought to be a key factor in the pathophysiology of diabetes mellitus.Damage to DNA and proteins can result in vascular problems such as nephropathy, neuropathy, retinopathy, and coronary heart disease.Therefore, the current study was aimed to assess the ethyl acetate, ethanol and aqueous extracts of Syzygium zeylanicum (L.) DC.For in vitro antioxidant and antidiabetic potential by DPPH, ABTS, ferric oxide reducing assay (FRAP), total antioxidant assay, -amylase assay and -glucosidase assay.For antioxidant activity, ethanolic extract showed significant IC 50 values (56.12 µg/ml for DPPH assay and 60.43 µg/ml for ABTS) comparing ethyl acetate and aqueous extracts.The ethanolic fraction had a greater -glucosidase inhibitory and -amylase inhibition effect (IC 50 values 69.92 µg/ml and 65.48 µg/ml, respectively) than other extracts when it came to antidiabetic activity.Based on the findings, S. zeylanicum leaves have antioxidant and antidiabetic properties.Additionally, ethanolic extract of S. zeylanicum may have more antioxidant and potential ingredients in diabetes prevention than other extracts.
Nair et al. (Mon,) studied this question.