Study of Peculiarities of Essential Oil Accumulation by the Wormwood Herb of the Synanthropic Flora of the Rostov Region

Introduction. At present, there is a growing interest in the use of medicinal plant raw materials in the pharmaceutical industry as a basis for the pro-duction of medicines. However, the process of formation and accumulation of biologically active substances in plants is associated with a number of environmental factors, including anthropogenic. The aim of the study was to investigate the peculiarities of essential oil accumulation in the wormwood herb harvested in the synanthropic flora of Morozovsky district of Rostov region. Material and Methods. Fourteen points of raw material harvesting were selected to study the content of essential oil in it. Isolation and determina-tion of the content of essential oil was carried out in accordance with FS.2.5.0033.15 "Artemisia bitter grass" and GPM.1.5.3.0010.15 "Determination of the content of essential oil in medicinal plant raw materials and herbal medicinal preparations". Results. All analyzed samples of plant raw materials were found to be benign in terms of essential oil content. The minimum essential oil content in one of the samples, only 0.01% higher than the lower numerical value set by the FS. This sample was collected along a country road with no traffic. The maximum amount of essential oil (0.44%) was obtained in a sample harvested in a control area devoid of anthropogenic impact and characterized by a large species diversity of medicinal plant raw materials represented by different groups of plants (trees, shrubs, herbs). In general, for samples harvested in urban areas, the essential oil content is low. Conclusion. This suggests a negative influence of anthropogenic impact, as well as the peculiarities of the growing area on the accumulation of es-sential oil in the wormwood herb.