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Plasma cell neoplasms are characterized by tumor proliferation of a clone of plasma cells secreting pathological immunoglobulin. The most common types of plasma cell tumor include multiple myeloma, its predecessor smoldering myeloma, monoclonal gammopathy of undetermined significance, as well as rare forms – solitary plasmacytoma and extramedullary lesions with minimal or no bone marrow involvement. Among extramedullary lesions, several forms are distinguished, some of which are associated with bone tissue, and others are extraosseous, located in soft tissues or affecting various organs. The article presents a rare clinical case of extramedullary lesions with minimal bone marrow changes in a 49-year-old female patient with monoclonal gammopathy of undetermined significance and rheumatoid arthritis. Literature data, clinical manifestations, features of diagnosis and therapy are presented.
Козич et al. (Fri,) studied this question.