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October 2, 2024Open Access

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The Role of General Acid Catalysis in the Mechanism of an Alkyl Transferase Ribozyme

TWTimothy J. WilsonUniversity of Dundee EMErika McCarthyRutgers, The State University of New Jersey ŞEŞölen EkesanRutgers, The State University of New Jersey

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Abstract

MTR1 is an in vitro-selected alkyl transferase ribozyme that transfers an alkyl group from

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The Role of General Acid Catalysis in the Mechanism of an Alkyl Transferase Ribozyme | Synapse

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Wilson et al. (Wed,) studied this question.

synapsesocial.com/papers/68e55ef0e2b3180350efc38c https://doi.org/https://doi.org/10.1021/acscatal.4c04571

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1Synthesis, deprotection, analysis and purification of RNA and ribosomes1995 · 396 citations
2Mixed deoxyribo- and ribo-oligonucleotides with catalytic activity1990 · 169 citations
3High yield selective 3′-silylation of ribonucleosides1981 · 55 citations
4The S box regulon: a new global transcription termination control system for methionine and cysteine biosynthesis genes in Gram‐positive bacteria1998 · 290 citations
5Structure and mechanism of a methyltransferase ribozyme2022 · 44 citations