A high cardiovascular health score, indicating greater adherence to Life's Essential 8 health behaviors, was associated with lower odds of hypertension (OR 0.32) in adolescents compared to a low score.
Cross-Sectional (n=3,941)
Does adherence to health behaviors defined in Life's Essential 8 reduce the odds of hypertension in adolescents?
Greater adherence to health behaviors defined in Life's Essential 8 is associated with significantly reduced odds of hypertension in adolescents, particularly among boys and those with overweight or obesity.
Effect estimate: OR 0.32 (95% CI 0.17-0.61)
p-value: p=<0.001
BACKGROUND: Hypertension is a common condition during adolescence with increasing prevalence globally, alongside the epidemic of unhealthy lifestyles and obesity. Health behaviors have been shown to be associated with hypertension risk in adults. Life's essential 8 (LE8), as a comprehensive indicator to evaluate cardiovascular health (CVH), includes 4 health factors and 4 health behaviors. This study aims to evaluate the association between health behaviors defined in LE8 and hypertension among adolescents. METHODS: Data of this study were extracted from the National Health and Nutrition Examination Surveys (NHANES) 2007-2018. Health behaviors of LE8 including diet, physical activity and tobacco smoke exposure. The outcome was the odd of hypertension in adolescents. The weighted univariate and multivariate logistic regression was unitized to explore the relationship between CVH score and hypertension in adolescents. Subgroup analysis and sensitivity analysis were further conducted to explore the association across different populations. RESULTS: Totally 3,941 adolescents aged 12-17 years were included, with the mean aged of 14.48 ± 0.04 years. Of whom, 203 (5.15%) had hypertension. After adjusted all covariates, high CVH score was associated with the lower odds of hypertension (OR = 0.32, 95%CI: 0.17-0.61), especially in boys (OR = 0.23, 95%CI: 0.11-0.51) and adolescents with overweight/obesity (OR = 0.24, 95%CI: 0.10-0.56). Sensitivity analysis reported that the association between CVH score and the odds of hypertension was also robust after excluding self-reported hypertension and medication taking (OR = 0.37, 95%CI: 0.18-0.74). CONCLUSION: A high CVH score, indicating a greater adherence of health behaviors, was associated with a reduced odds of hypertension, especially among boys and overweight/obesity adolescents. Large-scale prospective cohort studies are needed to further explore the association between health behaviors defined in LE8 and hypertension among adolescents.
Zhang et al. (Thu,) conducted a cross-sectional in Hypertension (n=3,941). High Cardiovascular Health (CVH) score vs. Low CVH score was evaluated on Odds of hypertension (OR 0.32, 95% CI 0.17-0.61, p=<0.001). A high cardiovascular health score, indicating greater adherence to Life's Essential 8 health behaviors, was associated with lower odds of hypertension (OR 0.32) in adolescents compared to a low score.
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