Rapidly evolving field of tricuspid interventions with multiple devices in trials.
Transcatheter tricuspid-valve replacement significantly improved symptoms and quality of life compared to medical therapy in patients with severe tricuspid regurgitation.
Does transcatheter tricuspid-valve replacement improve outcomes in patients with severe tricuspid regurgitation compared to medical therapy alone?
Patients with severe tricuspid regurgitation
Transcatheter tricuspid-valve replacement
Medical therapy alone
Primary composite outcomecomposite
Transcatheter tricuspid-valve replacement is superior to medical therapy alone for improving symptoms and quality of life in patients with severe tricuspid regurgitation.
For patients with severe tricuspid regurgitation, transcatheter tricuspid-valve replacement was superior to medical therapy alone for the primary composite outcome, driven primarily by improvements in symptoms and quality of life. (Funded by Edwards Lifesciences; TRISCEND II ClinicalTrials.gov number, NCT04482062.).
“While neither trial demonstrated a mortality benefit, these two trials showed that both T-TEER and TTVR were associated with a reduction in TR, reduction of symptoms and improvement in quality of life compared to medical therapy alone.”
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Rebecca T. Hahn
Raj Makkar
Vinod H. Thourani
New England Journal of Medicine
Stanford University
Northwestern University
Cleveland Clinic
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Hahn et al. (Wed,) reported a other. Transcatheter tricuspid-valve replacement significantly improved symptoms and quality of life compared to medical therapy in patients with severe tricuspid regurgitation.
www.synapsesocial.com/papers/6962d05361a150f4f4f82b1d — DOI: https://doi.org/10.1056/nejmoa2401918