Does the Naples Prognostic Score predict no-reflow phenomenon in patients undergoing saphenous vein graft PCI?
The Naples Prognostic Score demonstrates strong discriminative ability (AUC 0.888) for predicting the no-reflow phenomenon during saphenous vein graft PCI.
BACKGROUND: No-reflow is a critical adverse event associated with percutaneous coronary intervention (PCI), particularly during saphenous vein graft (SVG) procedures. The Naples Prognostic Score (NPS) reflects inflammatory status, but its relationship with no-reflow remains unclear. Therefore, we aimed to evaluate the relationship between NPS and no-reflow occurrence following SVG PCI. METHODS: We retrospectively analyzed 286 patients who underwent SVG PCI from January 2020 to January 2024, with a median age of 65 years and 85.7% male. Participants were categorized into low NPS (0-2, 48.6%) and high NPS (3-4, 51.4%) groups. Two nested models were developed by adding NPS (continuous and categorical, respectively) to the base model. RESULTS: : 0.468) and discriminative ability (AUC: 0.888). CONCLUSION: Our findings suggest that NPS is a strong predictor of no-reflow following SVG PCI.
Yılmaz et al. (Sun,) studied this question.