Pulse Explore Journal Club Debates Trending Researchers

Join discussions, follow papers, and never miss your next session.

Download on theApp Store

Home Explore Journal Club Trending

⌘+K

Research Paper | Synapse

June 3, 2025Open Access

View Full Paper

Monovalent mRNA XBB.1.5 vaccine effectiveness against COVID-19 hospitalization in Quebec, Canada: Impact of variant replacement and waning protection during 10-month follow-up

SCSara CarazoCentre hospitalier universitaire de Québec DSDanuta M. SkowronskiUniversity of British Columbia NBNicholas BrousseauInstitut National de Santé Publique du Québec

Key Points

Key points are not available for this paper at this time.

Abstract

Among individuals aged 60 years or older, mRNA XBB-vaccination provided meaningful, albeit limited to first four months post-vaccination, protection against COVID-19 hospitalization due to XBB, JN and KP subvariants. Better vaccines are needed to effectively protect older adults against COVID-19 hospitalizations.

Ask AI

Helpful

Bookmark

Share

View Full Paper

Ask AI

Helpful

Bookmark

Share

View Full Paper

Cite This Study

Carazo et al. (Tue,) studied this question.

synapsesocial.com/papers/69dabecd7a67537a8ba3c4df https://doi.org/https://doi.org/10.1371/journal.pone.0325269

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Effectiveness of the BNT162b2 XBB.1.5-adapted vaccine against COVID-19 hospitalization related to the JN.1 variant in Europe: a test-negative case-control study using the id.DRIVE platform2024 · 19 citations
2Impact of chronic comorbidities on hospitalization, intensive care unit admission and death among adult vaccinated and unvaccinated COVID-19 confirmed cases during the Omicron wave2023 · 8 citations
3Estimated Effectiveness of the BNT162b2 XBB Vaccine Against COVID-192024 · 52 citations
4Effectiveness of XBB.1.5 Monovalent COVID‐19 Vaccines During a Period of XBB.1.5 Dominance in EU/EEA Countries, October to November 2023: A VEBIS‐EHR Network Study2024 · 35 citations
5Depletion-of-susceptibles bias in influenza vaccine waning studies: how to ensure robust results2019 · 59 citations