Supplementary Figure S6 from T-cell Dependency of Tumor Regressions and Complete Responses with RAS(ON) Multi-selective Inhibition in Preclinical Models of Pancreatic Ductal Adenocarcinoma

Key Points

• The study highlights the role of t cells in tumor regressions influenced by RAS(ON) inhibition.
• Findings reveal alterations in t cell phenotypes within tumor-draining lymph nodes following treatment.
• Preclinical models of pancreatic ductal adenocarcinoma were used to assess the effects of the intervention.
• Understanding these mechanisms may enhance cancer treatment targeting tumor immunity and response.

Abstract