What type of study is this?

This is a In Vitro Study study (also classified as: Observational).

August 18, 2025Open Access

Figure 7 from PSA Secretion from Single Circulating Tumor Cells of Metastatic Castration-Naïve Prostate Cancer Patients

Key Points

PSA-secreting circulating tumor cells were identified, revealing their potential role in prostate cancer monitoring.
Out of all captured cells, the presence of PSA-positive and PSMA-positive cells were analyzed, with specific attention to nanowell distribution.
Assessment was based on the capture of circulating tumor cells using nanowells and SPOT software for detection.
Findings highlight the need for further exploration of circulating tumor cells in metastatic prostate cancer diagnostics.

Abstract

Distribution of CTC groups in the nanowells. A, Percentage of PSA-secreting and non-secreting cells detected in the nanowells and analyzed using the SPOT software. B, Percentage of PSMA+ and PSMA− cells identified in the nanowells. There were 0 CTC captured in the nanowells of the first three DLA. The total CTC counts in the nanowells are represented for each patient above the columns.

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