Figure S4 from Genome-Wide CRISPR Screening Reveals That mTOR Inhibition Initiates Ferritinophagy and Ferroptosis in Head and Neck Cancer

Key Points

• mTOR inhibition triggers ferroptosis, potentially aiding cancer treatment.
• Key evidence shows mTOR inhibition leads to significant ferroptosis in head and neck cancer cells.
• Observational analysis demonstrates the link between mTOR inhibition and ferritinophagy activation.
• These findings may enable new therapeutic strategies for head and neck cancer treatment.