Abstract Pneumatosis intestinalis (PI), the presence of gas within the bowel wall, is a rare but significant finding in cancer patients, often resulting from multifactorial etiologies such as bowel ischemia, chemotherapy, immunosuppression, and infections. This article presents a series of cases illustrating the diverse clinical presentations and management strategies for PI in this patient population. In some cases, PI was an incidental, asymptomatic finding, managed conservatively with bowel rest and monitoring. In others, PI was associated with severe complications such as bowel ischemia and sepsis, requiring urgent surgical intervention and intensive care. These cases highlight the importance of early detection, careful monitoring, and tailored interventions in managing PI in cancer patients. Understanding the complex interplay between cancer treatments and gastrointestinal health is essential to prevent serious complications and optimize patient outcomes.
Pearce et al. (Thu,) studied this question.
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