ABSTRACT Objective: To compare the international BMI standard/references of the International Obesity Task Force (IOTF), MULT, and the World Health Organization (WHO) and to analyze the association between changes in BMI growth channeling (BMI-GC) during childhood and the risk of being overweight in early adolescence. Design: Participant data from the Millennium Cohort Study (MCS), Young Lives (YL), and Generation XXI (G21) cohorts were obtained at three time points. Lin’s concordance coefficient (CCC) and the weighted Kappa coefficient were used to assess the agreement among the BMI standard/references. The relative risk (RR) of being overweight at 9.5-13.5y, based on an increase in BMI-GC (amplitude ≥0.67) between 3.5-6y and 6.5-9y, was calculated, with estimates adjusted for sex, ethnicity, and socioeconomic status. Setting: Ethiopia, India, Portugal, Vietnam, and United Kingdom. Participants: 12 624 participants from the MCS, YL, and G21 studies. Results: The prevalence of overweight across the three ages groups was higher when using the WHO standard/reference (12.8-25.9%) compared to the MULT (17.1-22.9%), and IOTF (13.0-19.3%) references. However, substantial agreement (0.95 < CCC ≤ 0.99) was found among these standard/references. Children who increased their BMI-GC by ≥0.67 and <0.86 were more likely to be overweight at 9.5-13.5y MULT-RR=2.49,95%CI:2.00-3.09/ WHO-RR=2.47,95%CI:1.96-3.12/ IOTF-RR=2.31,95%CI:1.82-2.93, compared to those who have stayed in their BMI-GC. Conclusions: A change in the BMI-GC among normal-weight children during childhood was associated with a significantly higher risk of being overweight at 9.5-13.5y. These findings suggest that monitoring BMI-GC in children could be a tool to intervene and to prevent overweight in early adolescence.
Oliveira et al. (Fri,) studied this question.