Fungal strains were isolated from siol, and Aspergillus terreus was identified using the Internal Transcribed Spacer (ITS) molecular diagnostic technique. The biodegradation potential of this fungus was evaluated against three expired pharmaceutical raw materials: Clopidogrel, Paracetamol, and Rosuvastatin, all provided by Pioneer Pharmaceuticals, Iraq–Sulaymaniyah. Among the tested compounds, Rosuvastatin exhibited the highest degradation rate at 82.77%, followed by Clopidogrel at 66.6%, and Paracetamol at 45.61%. Secondary metabolites produced by A. terreus were analyzed using Gas Chromatography–Mass Spectrometry (GC-MS). The most abundant compound identified was Cyclohexanemethanol, chlorodifluoroacetate, accounting for 31.81% of the total area. Other notable metabolites included 3,4-Dihydroxy-5-methyl-dihydrofuran-2-one (25.90%) and D-Glucohexodialdose (18.20%).
Shukry et al. (Mon,) studied this question.
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